簡要描述：StemRD GDC-0449, SMO antagonist 拮抗劑
GDC-0449 （Vismodegib）: A potent antagonist of SMO （smoothened）. This small molecule compound is a hedgehog pathway inhibitor by directly binding to SMO. This molec

產(chǎn)品英文名稱: GDC-0449, SMO Antagonist
產(chǎn)品中文名稱: GDC-0449, SMO 拮抗劑

GDC-0449, SMO Antagonist 產(chǎn)品英文簡述:
GDC-0449 (Vismodegib): A potent antagonist of SMO (smoothened). This small molecule compound is a hedgehog pathway inhibitor by directly binding to SMO. This molecule has been developed by Genentech for clinical application against hedgehog-dependent cancers.
 
Purity: Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the Gli-1 reporter gene, this compound gives IC50 of 5-20 nM.

華雅再生醫(yī)學(xué)工程技術(shù)有限公司是一家為干細(xì)胞研究員提供干細(xì)胞無血清培養(yǎng)基，支原體檢測試劑盒，心肌細(xì)胞株，人間充質(zhì)干細(xì)胞株，凍存管凍存盒，臍帶間充質(zhì)干細(xì)胞凍存袋，細(xì)胞實(shí)驗(yàn)耗材等進(jìn)口品牌高質(zhì)量產(chǎn)品。專注干細(xì)胞研究，關(guān)注干細(xì)胞治療產(chǎn)品，購買干細(xì)胞產(chǎn)品請到華雅再生醫(yī)學(xué)工程公司。